Wonderland: Shapes & Illnesses

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At first glance, you might think that this drawing is that of a mandala or some mathematical shape which I am so fond of. But actually, it is a diagrammatic representation of the Barr-Epstein virus.

Virus symmetry is one of the most beautiful, naturally occurring structures of nature. Though incredibly tiny (the smallest animal virus is the one that causes foot-and-mouth disease at 20nm), viron symmetry is highly structured and falls into highly organised categories: helical, polyhedral (cubical) and binal symmetry.

Not so bacterium structures which sometimes look like primitive spaceship.

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My daughter who is studying Biology for her International Baccalaureate commented dourly that there is so much stuff to learn for this subject. I don’t want her to just memorise stuff, but to be excited by the knowledge (or else the three years of preclinical medical course would be hellishly long for her).

So relating virus and bacteria to us and our daily lives:

Virus and bacteria cause infection in the body. When their presence is detected, the body switches on its inflammatory response, which is its strategy for fighting infection. However, inflammation can kill, though it was meant to be our body’s lifesaving strategy.

But here’s the useful piece of information that you might not previously know: virus and bacteria cause different types of inflammatory responses. Studies done at Yale University by Ruslan Medzhitov showed that a body recovering from colds (often caused by viruses) benefit from feeding, whilst those suffering from fever (typically caused by bacteria) should be starved, especially of carbohydrates which breaks down into glucose. For me, this is a really exciting discovery because it means that Medicine can move forward from blanket prescription of antibiotics – which does not work in many cases anyway – to a wellbeing system of managing health through nutrition.
The old adage of feeding the cold and starving the fever seems to be on its way to be proven ‘true’ by modern scientific establishment.

In the meantime, I leave you with some viruses.

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Note: In my novella which will be published on the 21st November 2016, An Evening in Wonderland – A Brief Story of Maths, Physics & The Universe (suitable for young adults), the protagonist Alice Liddell urged her beloved Professor to close his eyes and look for the symmetries in the world within and also out there in the universe, for within the shapes lie the truth that he was seeking.

You can read an interview with Ruzlan Medzhitov in the New York Times by clicking on the link here.

Why We Want To Raise Lifelong Learners

A few weeks ago, whilst choosing books on Amazon to take along on my honeymoon, I bought Professor Mary Beard’s A History of Ancient Rome. I bought the book simply because it was on Amazon’s bestseller list, but to my surprise, I really enjoyed it. I finished the whole book even before the plane landed. It was a surprise, because the British education system forces us to make a choice about our future at the tender age of 16, when we have to choose which three or four subjects to study for A levels. These three or four subjects are the precursors of our University course two years later and our career path three years on.

I did Physics, Mathematics and Chemistry. I abandoned Geography, History, Literature, Languages, Art and Humanities a long time ago, because they were not in my school curriculum. Being not inclined academically, I struggled with the rigours of getting good grades for three A level subjects, and alongside partying, chilling out on the beach and being a teenager generally, I did not have the time nor the inclination to broaden my knowledge base. Later, a demanding career and children meant that I had very little mental capacity to indulge in frivolous pastimes, which learning unrelated subjects was considered as in my overloaded life.

But my love of learning never left me. I owe it all to my mother, my first teacher. She never minded that I did not get good grades and showed me, over the years, that it made no difference to her whatsoever that her daughter was at the bottom of the exam results table. She was happy with the daughter she had and she delighted in raising me. The stuff she invested her time in teaching my brothers and I were never related to schoolwork. It was always about the magic of the world around us.

It is a wonderful gift to be raised as a lifelong learner, because my mother has given me eyes that are open to beauty and wonder, however harsh and difficult reality and life is. It doesn’t take me much – just a deep breath and a heartbeat – to remember my magical times with my mother. When I was choosing a honeymoon location, I chose somewhere not far from my home: Isle of Wight. I could have chosen half a dozen exotic locations, but I chose the Isle of Wight. I remembered our many unforgettable seaside days.

And at 47, I was delighted to rediscover them with the man I am planning to share the rest of my life with. The windswept bridle paths and coastal roads that I loved as a teenager, the seaweeds that I know as well as the back of my hands and the fossils that delight me so. On our honeymoon, I showed Thomas a part of me that he could not find anywhere else, with anyone else, except me. I showed him too, my fascination with cosmology (lying in bed, looking at Venus rising over the English Solent), the 11th dimension, mathematics and the warping of space-time that brought us, in the most unimaginable circumstances, into each other’s lives. The world around you is full of magic, if you open your eyes to it.

Thomas’s article on theoretical physics and business is here: http://agermanonthemove.blogspot.co.id/2015/10/the-heart-of-matter-metaphors-in_18.html?m=1

Across The Counties

Lionheart

Yesterday was officially the end of the British summer as the cold front came in with vengeance. Fierce storms, 70mph winds and driving rain were the forecast, and indeed, when I went out for dinner last night, the roads were relatively quiet as people opted to stay indoors. The forecast this morning was meant to be the same.

Overnight, there had been several fatalities on the road in southern England. This morning, at 6am, there was a massive accident on the M4 at Langley. There was a tailback going back 10 miles.

But over dinner last night, Knight had dared me to do something I have never done before: swim on the River Avon with him.  I have never swam on the Avon with anyone.  What a ridiculous suggestion. Because at the best of times, I hate swimming.  I am a strong swimmer based solely on this very dislike of the water – I swim fast, to get myself out of the water as fast as possible.  But to voluntarily swim on the swollen Avon on the first day of autumn? I must be mad.  Even my normally implacable mother had wailed, “But darling, people have drowned on the Avon!”

But meet Knight’s challenge I must.  After all, isn’t growth all about coming face to face with your inner boundaries, and stepping out of your comfort zone? it’s what keeps us young, as we draw new confidence and new exhilaration from taking the step off our usual daily existence.

So like two misbehaving teenagers, we set off from London at the crack of dawn on this supposedly vicious day to travel to Avon. To our surprise, the sun followed us throughout, with no sign of grey skies or dark clouds, as we drove past the roads of our past. We laughed joyously, and the years melted away.

Whilst at University (though at separate times) we were both members of the Oxford Stunt Factory. I joined, simply because I wanted to go to its Pink Pimms Party in the park after the May Ball. I ended up being catapulted across the river at 3am in the morning, still in my ball gown. After that, I was hooked and became the Club’s fixture.

River Avon is rich in history.  It is 75miles long, slow, meandering, with hidden dangers.  In the past (maybe 5,000BC), when it was young, it was a powerful torrent that the limestone outcrop could not push back. The river gradually wore away at the rock eventually forming the 300 feet deep gorge that is the seaward entrance to the city.

And it was into this river we jumped in, swam briefly, emerged with shivering bodies and chattering teeth, exhilarated, alive.

Warning: Do not attempt this. In April 2014, a man drowned on the same spot on the Avon that we swam in. 

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Same view, different eyes

A year after I graduated from Oxford, my family remained in our Oxford house whilst I started work in London. I had to commute. It was a nightmare, but there was no way out. Housing in London (where I wanted to live) has always been exorbitantly expensive, and I was the main breadwinner. We also had lots of children.  So. for almost a year, I had to endure the long commute.  I could not afford to commute by train, because a huge chunk of my salary would have gone to British Rail. The bus would have been too slow. I had no choice but to bike it. My machine was a Ducati Monster, which was a thrill to ride buy quite unreliable.  And it was hellish on winter nights. I just wanted to rush home either to put my kids to bed or to have breakfast with them, depending on my shift.  Life wasn’t easy then.

Thus, I travelled on these roads for over a year without noticing how beautiful they are.  Today, I did.

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The strength of a nation

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Avon and Somerset, Oxfordshire and London. We set off at 6am, and caught the morning sun burning the mists off the grounds in Oxfordshire. We both have great fondness for this county, because Oxford is our alma mater. We had a lot of lovely memories here, punting on the Isis and Cherwell in summer, pubs of St Giles in winter, the higgledy piggledy bookshop on St Giles, friends’ houses in Jericho and summer parties on our colleges’ quads. It was a magical interlude before ‘real’ life began.

We drove on, passing rolling farmlands and pastures, fields ready for winter cereal or those with tall corn already growing. We drove past deer, horses, cows and sheep. The leaves are starting to turn auburn and gold at this time of the year. It is this that deeply binds Englishmen and Englishwomen to our country rather than the glitter and opportunities of the capital. I hope my son will return after his 6 month tour of duty of the Middle East back to his beloved England once more. He promised me he would do his best to come home, and to bring others safely home too. We have one Englishman whose time is running out, a John Cantlie. My son said, it is worth the sacrifice of his own life and others like him to bring John Cantlie home, because all the British men and women involved had gone into this voluntarily, with their eyes wide open, willing to make the ultimate sacrifice.

“We will never leave one of our own behind, Mum,” my 25 year old Lieutenant said. “It’s not machismo, but a simple ideology.”

My boy is young, passionate, idealistic, fiery and so proud to be English. Someday, he will make a fine leader. But as his mother, I just want him home where he belongs. Here, in England.

Knight touched my hand lightly as we drove into the capital at nightfall. We had driven in silence for the last few miles and I had tears running down my cheeks.

“What I said in my speech just now, though I misquoted slightly, is something you have shown me,” he said. “That you can judge the strength of a nation by the face of its women.”

And through my tears, I smiled for him and my son.